4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one
TL;DR: 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one (CAS 312507-18-9) is a chemical compound with molecular formula C25H20FNO3 and molecular weight 401.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(2-phenylethyl)pyrrolidine-2,3-dione
Also Known As: 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one, (4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-phenethylpyrrolidine-2,3-dione, 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one, 5-(4-fluorophenyl)-3-hydroxy-4-(phenylcarbonyl)-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C25H20FNO3 |
|---|---|
| Molecular Weight | 401.14 g/mol |
| LogP | 4.4901 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 401.14273 |
| Heavy Atoms | 30 |
| Complexity | 1092.2572 |
Chemical Identifiers
| CAS Number | 312507-18-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)CCN2C(/C(=C(/C3=CC=CC=C3)\O)/C(=O)C2=O)C4=CC=C(C=C4)F |
Product Overview
4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one (CAS 312507-18-9), with molecular formula C25H20FNO3 and molecular weight 401.14 g/mol. IUPAC: (4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(2-phenylethyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one
Property Insights of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one
The XLogP value of 4.4901 indicates that 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one?
The CAS number of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one is 312507-18-9.
What is the molecular formula of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one?
The molecular formula of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one is C25H20FNO3.
What is the molecular weight of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one?
The molecular weight of 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one is 401.14 g/mol.
Where can I buy 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one?
You can request a quote for 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-phenethyl-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.