![N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide structure](/static/products/312/312504-04-4.png)
N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
TL;DR: N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide (CAS 312504-04-4) is a chemical compound with molecular formula C17H11F3N8O4S and molecular weight 480.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-(1-methyl-4-nitropyrazole-3-carbonyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
Also Known As: N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-(1-methyl-4-nitro-1H-pyrazole-3-carbonyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-(1-methyl-4-nitropyrazole-3-carbonyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-[(1-methyl-4-nitro-1H-pyrazol-3-yl)carbonyl]-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-[(1-methyl-4-nitro-1H-pyrazol-3-yl)carbonyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
| Molecular Formula | C17H11F3N8O4S |
|---|---|
| Molecular Weight | 480.06 g/mol |
| LogP | 2.1931 |
| Topological Polar Surface Area | 149.35 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 480.05762 |
| Heavy Atoms | 33 |
| Complexity | 1393.4037 |
Chemical Identifiers
| CAS Number | 312504-04-4 |
|---|---|
| SMILES | CN1C=C(C(=N1)C(=O)NNC(=O)C2=NN3C(=CC(=NC3=C2)C4=CC=CS4)C(F)(F)F)[N+](=O)[O-] |
Product Overview
N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide (CAS 312504-04-4), with molecular formula C17H11F3N8O4S and molecular weight 480.06 g/mol. IUPAC: N'-(1-methyl-4-nitropyrazole-3-carbonyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide.
Chemical Property Profile of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
Property Insights of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
The XLogP value of 2.1931 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide. The TPSA of 149.35 Ų indicates high polarity, suggesting N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide?
The CAS number of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide is 312504-04-4.
What is the molecular formula of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide?
The molecular formula of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide is C17H11F3N8O4S.
What is the molecular weight of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide?
The molecular weight of N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide is 480.06 g/mol.
Where can I buy N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide?
You can request a quote for N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-({4-nitro-1-methyl-1H-pyrazol-3-yl}carbonyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.