4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one
TL;DR: 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one (CAS 312272-63-2) is a chemical compound with molecular formula C14H11F3N2O3 and molecular weight 312.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-6-(trifluoromethyl)-1H-pyrimidin-2-one
Also Known As: 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one, 2(1H)-Pyrimidinone,4-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-6-(trifluoromethyl)-, 4-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-6-(trifluoromethyl)-1H-pyrimidin-2-one
| Molecular Formula | C14H11F3N2O3 |
|---|---|
| Molecular Weight | 312.07 g/mol |
| LogP | 2.6733 |
| Topological Polar Surface Area | 75.21 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 312.07217 |
| Heavy Atoms | 22 |
| Complexity | 766.6589 |
Chemical Identifiers
| CAS Number | 312272-63-2 |
|---|---|
| SMILES | COC1=C(C=CC(=C1)C=CC2=NC(=O)NC(=C2)C(F)(F)F)O |
Product Overview
4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one (CAS 312272-63-2), with molecular formula C14H11F3N2O3 and molecular weight 312.07 g/mol. IUPAC: 4-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-6-(trifluoromethyl)-1H-pyrimidin-2-one.
Chemical Property Profile of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one
Property Insights of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one
The XLogP value of 2.6733 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one. The TPSA of 75.21 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one. Following Lipinski's Rule of Five, 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one?
The CAS number of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one is 312272-63-2.
What is the molecular formula of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one?
The molecular formula of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one is C14H11F3N2O3.
What is the molecular weight of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one?
The molecular weight of 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one is 312.07 g/mol.
Where can I buy 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one?
You can request a quote for 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Hydroxy-3-methoxystyryl)-6-(trifluoromethyl)pyrimidin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.