(E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide
TL;DR: (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide (CAS 311809-81-1) is a chemical compound with molecular formula C18H15ClN4O2 and molecular weight 354.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chlorophenyl)-4-[(2-hydroxyphenyl)methylideneamino]-1-methylpyrazole-5-carboxamide
Also Known As: (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide, N-(3-chlorophenyl)-2-methyl-4-[(6-oxocyclohexa-2,4-dien-1-ylidene)methylamino]pyrazole-3-carboxamide, N-(3-chlorophenyl)-2-methyl-4-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]pyrazole-3-carboxamide, N-(3-chlorophenyl)-2-methyl-4-[[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]pyrazole-3-carboxamide, N-(3-chlorophenyl)-4-{[(E)-(2-hydroxyphenyl)methylidene]amino}-1-methyl-1H-pyrazole-5-carboxamide
| Molecular Formula | C18H15ClN4O2 |
|---|---|
| Molecular Weight | 354.09 g/mol |
| LogP | 3.782 |
| Topological Polar Surface Area | 79.51 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 354.08835 |
| Heavy Atoms | 25 |
| Complexity | 949.754 |
Chemical Identifiers
| CAS Number | 311809-81-1 |
|---|---|
| SMILES | CN1C(=C(C=N1)N=CC2=CC=CC=C2O)C(=O)NC3=CC(=CC=C3)Cl |
Product Overview
(E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide (CAS 311809-81-1), with molecular formula C18H15ClN4O2 and molecular weight 354.09 g/mol. IUPAC: N-(3-chlorophenyl)-4-[(2-hydroxyphenyl)methylideneamino]-1-methylpyrazole-5-carboxamide.
Chemical Property Profile of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide
Property Insights of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide
The XLogP value of 3.782 indicates that (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.51 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide. Following Lipinski's Rule of Five, (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide?
The CAS number of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide is 311809-81-1.
What is the molecular formula of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide?
The molecular formula of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide is C18H15ClN4O2.
What is the molecular weight of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide?
The molecular weight of (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide is 354.09 g/mol.
Where can I buy (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide?
You can request a quote for (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(3-chlorophenyl)-4-((2-hydroxybenzylidene)amino)-1-methyl-1H-pyrazole-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.