![7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol structure](/static/products/3082/308294-73-7.webp)
7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol
TL;DR: 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol (CAS 308294-73-7) is a chemical compound with molecular formula C20H15FN4O and molecular weight 346.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-[(4-fluorophenyl)-(pyrimidin-2-ylamino)methyl]quinolin-8-ol
Also Known As: 7-[(4-fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol, 8-Quinolinol, 7-[(4-fluorophenyl)(2-pyrimidinylamino)methyl]-, 7-[(4-Fluorophenyl)(2-pyrimidinylamino)methyl]-8-quinolinol, 7-[(4-fluorophenyl)-(pyrimidin-2-ylamino)methyl]quinolin-8-ol, 7-[(4-fluorophenyl)[(pyrimidin-2-yl)amino]methyl]quinolin-8-ol
| Molecular Formula | C20H15FN4O |
|---|---|
| Molecular Weight | 346.12 g/mol |
| LogP | 4.071 |
| Topological Polar Surface Area | 70.93 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 346.123 |
| Heavy Atoms | 26 |
| Complexity | 1038.5476 |
Chemical Identifiers
| CAS Number | 308294-73-7 |
|---|---|
| SMILES | C1=CC2=C(C(=C(C=C2)C(C3=CC=C(C=C3)F)NC4=NC=CC=N4)O)N=C1 |
Product Overview
7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol (CAS 308294-73-7), with molecular formula C20H15FN4O and molecular weight 346.12 g/mol. IUPAC: 7-[(4-fluorophenyl)-(pyrimidin-2-ylamino)methyl]quinolin-8-ol.
Chemical Property Profile of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol
Property Insights of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol
The XLogP value of 4.071 indicates that 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.93 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol. Following Lipinski's Rule of Five, 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol?
The CAS number of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol is 308294-73-7.
What is the molecular formula of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol?
The molecular formula of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol is C20H15FN4O.
What is the molecular weight of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol?
The molecular weight of 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol is 346.12 g/mol.
Where can I buy 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol?
You can request a quote for 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol?
Yes, KEHONG BIO provides custom synthesis services for 7-[(4-Fluorophenyl)(pyrimidin-2-ylamino)methyl]quinolin-8-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.