LMP744
TL;DR: LMP744 (CAS 308246-52-8) is a chemical compound with molecular formula C24H24N2O7 and molecular weight 452.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
20-[3-(2-hydroxyethylamino)propyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione
Also Known As: LMP744, LMP744 free base, MJ-III-65, MJ-III65, Topoisomerase-1 inhibitor lmp744
| Molecular Formula | C24H24N2O7 |
|---|---|
| Molecular Weight | 452.16 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 107.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 452.15836 |
| Heavy Atoms | 33 |
| Complexity | 802.0 |
Chemical Identifiers
| CAS Number | 308246-52-8 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCNCCO)OC |
| InChIKey | QCSDJDQOJBQTDV-UHFFFAOYSA-N |
Product Overview
LMP744 (CAS 308246-52-8), with molecular formula C24H24N2O7 and molecular weight 452.16 g/mol. IUPAC: 20-[3-(2-hydroxyethylamino)propyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione.
Chemical Property Profile of LMP744
Property Insights of LMP744
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for LMP744. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for LMP744. Following Lipinski's Rule of Five, LMP744 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of LMP744?
The CAS number of LMP744 is 308246-52-8.
What is the molecular formula of LMP744?
The molecular formula of LMP744 is C24H24N2O7.
What is the molecular weight of LMP744?
The molecular weight of LMP744 is 452.16 g/mol.
Where can I buy LMP744?
You can request a quote for LMP744 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for LMP744?
Yes, KEHONG BIO provides custom synthesis services for LMP744 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.