N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
TL;DR: N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide (CAS 307952-89-2) is a chemical compound with molecular formula C18H17F2NO4 and molecular weight 349.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
Also Known As: N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide, N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide, (2E)-N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
| Molecular Formula | C18H17F2NO4 |
|---|---|
| Molecular Weight | 349.11 g/mol |
| LogP | 3.6425 |
| Topological Polar Surface Area | 56.79 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 349.11258 |
| Heavy Atoms | 25 |
| Complexity | 780.6533 |
Chemical Identifiers
| CAS Number | 307952-89-2 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C=CC(=O)NC2=C(C=C(C=C2)F)F |
Product Overview
N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide (CAS 307952-89-2), with molecular formula C18H17F2NO4 and molecular weight 349.11 g/mol. IUPAC: N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide.
Chemical Property Profile of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
Property Insights of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
The XLogP value of 3.6425 indicates that N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.79 Ų, N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide?
The CAS number of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide is 307952-89-2.
What is the molecular formula of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide?
The molecular formula of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide is C18H17F2NO4.
What is the molecular weight of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide?
The molecular weight of N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide is 349.11 g/mol.
Where can I buy N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide?
You can request a quote for N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2,4-difluorophenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.