7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol
TL;DR: 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol (CAS 307540-52-9) is a chemical compound with molecular formula C21H22FN3O and molecular weight 351.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-[(4-fluorophenyl)-(4-methylpiperazin-1-yl)methyl]quinolin-8-ol
Also Known As: AF-399/14569043, 7-((4-fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol, 7-[(4-fluorophenyl)-(4-methylpiperazin-1-yl)methyl]quinolin-8-ol, 7-[(4-fluorophenyl)(4-methylpiperazin-1-yl)methyl]quinolin-8-ol, F0815-0044
| Molecular Formula | C21H22FN3O |
|---|---|
| Molecular Weight | 351.17 g/mol |
| LogP | 3.4163 |
| Topological Polar Surface Area | 39.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 351.17468 |
| Heavy Atoms | 26 |
| Complexity | 904.7782 |
Chemical Identifiers
| CAS Number | 307540-52-9 |
|---|---|
| SMILES | CN1CCN(CC1)C(C2=CC=C(C=C2)F)C3=C(C4=C(C=CC=N4)C=C3)O |
Product Overview
7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol (CAS 307540-52-9), with molecular formula C21H22FN3O and molecular weight 351.17 g/mol. IUPAC: 7-[(4-fluorophenyl)-(4-methylpiperazin-1-yl)methyl]quinolin-8-ol.
Chemical Property Profile of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol
Property Insights of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol
The XLogP value of 3.4163 indicates that 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.6 Ų, 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol?
The CAS number of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol is 307540-52-9.
What is the molecular formula of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol?
The molecular formula of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol is C21H22FN3O.
What is the molecular weight of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol?
The molecular weight of 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol is 351.17 g/mol.
Where can I buy 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol?
You can request a quote for 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol?
Yes, KEHONG BIO provides custom synthesis services for 7-((4-Fluorophenyl)(4-methylpiperazin-1-yl)methyl)quinolin-8-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.