3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one
TL;DR: 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one (CAS 307525-32-2) is a chemical compound with molecular formula C18H12N2O2S2 and molecular weight 352.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[4-hydroxy-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]indol-2-one
Also Known As: ChemDiv3_000658, BAS 00555996, 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one, (3Z)-3-[3-(3-methylphenyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]-1,3-dihydro-2H-indol-2-one, (Z)-5-(2-oxoindolin-3-ylidene)-2-thioxo-3-(m-tolyl)thiazolidin-4-one
| Molecular Formula | C18H12N2O2S2 |
|---|---|
| Molecular Weight | 352.03 g/mol |
| LogP | 2.64111 |
| Topological Polar Surface Area | 54.59 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 352.03403 |
| Heavy Atoms | 24 |
| Complexity | 1172.2148 |
Chemical Identifiers
| CAS Number | 307525-32-2 |
|---|---|
| SMILES | CC1=CC(=CC=C1)N2C(=C(SC2=S)C3=C4C=CC=CC4=NC3=O)O |
Product Overview
3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one (CAS 307525-32-2), with molecular formula C18H12N2O2S2 and molecular weight 352.03 g/mol. IUPAC: 3-[4-hydroxy-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]indol-2-one.
Chemical Property Profile of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one
Property Insights of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one
The XLogP value of 2.64111 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one. With a topological polar surface area (TPSA) of 54.59 Ų, 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one?
The CAS number of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one is 307525-32-2.
What is the molecular formula of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one?
The molecular formula of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one is C18H12N2O2S2.
What is the molecular weight of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one?
The molecular weight of 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one is 352.03 g/mol.
Where can I buy 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one?
You can request a quote for 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 3-(4-Oxo-2-thioxo-3-m-tolyl-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.