F0745-0543
TL;DR: F0745-0543 (CAS 307512-62-5) is a chemical compound with molecular formula C22H27N3OS2 and molecular weight 413.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(1-adamantyl)-2-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylsulfanyl)acetamide
Also Known As: F0745-0543, AF-399/37330015, N-(1-adamantyl)-2-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylsulfanyl)acetamide, N-(1-adamantyl)-2-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ylsulfanyl)acetamide, N-(adamantan-1-yl)-2-{8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5-tetraen-3-ylsulfanyl}acetamide
| Molecular Formula | C22H27N3OS2 |
|---|---|
| Molecular Weight | 413.16 g/mol |
| LogP | 4.7472 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 413.15955 |
| Heavy Atoms | 28 |
| Complexity | 901.96576 |
Chemical Identifiers
| CAS Number | 307512-62-5 |
|---|---|
| SMILES | C1CCC2=C(C1)C3=C(S2)N=CN=C3SCC(=O)NC45CC6CC(C4)CC(C6)C5 |
Product Overview
F0745-0543 (CAS 307512-62-5), with molecular formula C22H27N3OS2 and molecular weight 413.16 g/mol. IUPAC: N-(1-adamantyl)-2-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylsulfanyl)acetamide.
Chemical Property Profile of F0745-0543
Property Insights of F0745-0543
The XLogP value of 4.7472 indicates that F0745-0543 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, F0745-0543 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0745-0543 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0745-0543?
The CAS number of F0745-0543 is 307512-62-5.
What is the molecular formula of F0745-0543?
The molecular formula of F0745-0543 is C22H27N3OS2.
What is the molecular weight of F0745-0543?
The molecular weight of F0745-0543 is 413.16 g/mol.
Where can I buy F0745-0543?
You can request a quote for F0745-0543 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0745-0543?
Yes, KEHONG BIO provides custom synthesis services for F0745-0543 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.