Macowine
TL;DR: Macowine (CAS 307494-75-3) is a chemical compound with molecular formula C16H19NO3 and molecular weight 273.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,10R,12R)-4-methoxy-9-azatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6,13-tetraene-5,12-diol
Also Known As: Macowine, 8-demethylmaritidine, (4aR,10bS)-Normaritidine, (10bS, 4aR)-normaritidine, 3H,6H-5,10b-ethanophenanthridine-3,8-diol, 4,4a-dihydro-9-methoxy-, (3R,4aR,10bS)-
| Molecular Formula | C16H19NO3 |
|---|---|
| Molecular Weight | 273.14 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.1365 |
| Heavy Atoms | 20 |
| Complexity | 426.0 |
Chemical Identifiers
| CAS Number | 307494-75-3 |
|---|---|
| SMILES | COC1=C(C=C2CN3CC[C@@]4([C@H]3C[C@H](C=C4)O)C2=C1)O |
| InChIKey | TZTBAJFJEZRQCV-IUIKQTSFSA-N |
Product Overview
Macowine (CAS 307494-75-3), with molecular formula C16H19NO3 and molecular weight 273.14 g/mol. IUPAC: (1S,10R,12R)-4-methoxy-9-azatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6,13-tetraene-5,12-diol.
Chemical Property Profile of Macowine
Property Insights of Macowine
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Macowine. With a topological polar surface area (TPSA) of 52.9 Ų, Macowine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Macowine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Macowine?
The CAS number of Macowine is 307494-75-3.
What is the molecular formula of Macowine?
The molecular formula of Macowine is C16H19NO3.
What is the molecular weight of Macowine?
The molecular weight of Macowine is 273.14 g/mol.
Where can I buy Macowine?
You can request a quote for Macowine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Macowine?
Yes, KEHONG BIO provides custom synthesis services for Macowine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.