![N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine structure](/static/products/307/307348-50-1.png)
N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine
TL;DR: N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine (CAS 307348-50-1) is a chemical compound with molecular formula C18H19ClFN3 and molecular weight 331.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(2-chloro-6-fluorophenyl)-N-[4-(4-methylphenyl)piperazin-1-yl]methanimine
Also Known As: (E)-N-(2-chloro-6-fluorobenzylidene)-4-(p-tolyl)piperazin-1-amine, 1-(2-chloro-6-fluorophenyl)-N-[4-(4-methylphenyl)piperazin-1-yl]methanimine, N-(2-CHLORO-6-FLUOROBENZYLIDENE)-4-(4-METHYLPHENYL)-1-PIPERAZINAMINE, N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine
| Molecular Formula | C18H19ClFN3 |
|---|---|
| Molecular Weight | 331.13 g/mol |
| LogP | 3.94362 |
| Topological Polar Surface Area | 18.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 331.12515 |
| Heavy Atoms | 23 |
| Complexity | 671.6629 |
Chemical Identifiers
| CAS Number | 307348-50-1 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2CCN(CC2)/N=C/C3=C(C=CC=C3Cl)F |
Product Overview
N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine (CAS 307348-50-1), with molecular formula C18H19ClFN3 and molecular weight 331.13 g/mol. IUPAC: (E)-1-(2-chloro-6-fluorophenyl)-N-[4-(4-methylphenyl)piperazin-1-yl]methanimine.
Chemical Property Profile of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine
Property Insights of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine
The XLogP value of 3.94362 indicates that N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.84 Ų, N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine?
The CAS number of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine is 307348-50-1.
What is the molecular formula of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine?
The molecular formula of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine is C18H19ClFN3.
What is the molecular weight of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine?
The molecular weight of N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine is 331.13 g/mol.
Where can I buy N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine?
You can request a quote for N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine?
Yes, KEHONG BIO provides custom synthesis services for N-[(E)-(2-chloro-6-fluorophenyl)methylidene]-4-(4-methylphenyl)piperazin-1-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.