4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine
TL;DR: 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine (CAS 307347-56-4) is a chemical compound with molecular formula C18H18F3N3 and molecular weight 333.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4-phenylpiperazin-1-yl)-1-[2-(trifluoromethyl)phenyl]methanimine
Also Known As: (E)-4-phenyl-N-(2-(trifluoromethyl)benzylidene)piperazin-1-amine, 4-PHENYL-N-(2-(TRIFLUOROMETHYL)BENZYLIDENE)-1-PIPERAZINAMINE, 4-phenyl-N-{(E)-[2-(trifluoromethyl)phenyl]methylidene}piperazin-1-amine, N-(4-phenylpiperazin-1-yl)-1-[2-(trifluoromethyl)phenyl]methanimine
| Molecular Formula | C18H18F3N3 |
|---|---|
| Molecular Weight | 333.15 g/mol |
| LogP | 3.8615 |
| Topological Polar Surface Area | 18.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 333.1453 |
| Heavy Atoms | 24 |
| Complexity | 690.1552 |
Chemical Identifiers
| CAS Number | 307347-56-4 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)/N=C/C3=CC=CC=C3C(F)(F)F |
Product Overview
4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine (CAS 307347-56-4), with molecular formula C18H18F3N3 and molecular weight 333.15 g/mol. IUPAC: (E)-N-(4-phenylpiperazin-1-yl)-1-[2-(trifluoromethyl)phenyl]methanimine.
Chemical Property Profile of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine
Property Insights of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine
The XLogP value of 3.8615 indicates that 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.84 Ų, 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine?
The CAS number of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine is 307347-56-4.
What is the molecular formula of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine?
The molecular formula of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine is C18H18F3N3.
What is the molecular weight of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine?
The molecular weight of 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine is 333.15 g/mol.
Where can I buy 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine?
You can request a quote for 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-Phenyl-N-(2-(trifluoromethyl)benzylidene)-1-piperazinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.