(E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
TL;DR: (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one (CAS 307342-99-0) is a chemical compound with molecular formula C15H16BrN3OS and molecular weight 365.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-bromophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
Also Known As: (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one, (5E)-5-[(4-bromophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one, 5-[(4-bromophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one, (5E)-5-[(4-BROMOPHENYL)METHYLIDENE]-2-(4-METHYLPIPERAZIN-1-YL)-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
| Molecular Formula | C15H16BrN3OS |
|---|---|
| Molecular Weight | 365.02 g/mol |
| LogP | 2.6668 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 365.01974 |
| Heavy Atoms | 21 |
| Complexity | 603.8497 |
Chemical Identifiers
| CAS Number | 307342-99-0 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC(=O)/C(=C\C3=CC=C(C=C3)Br)/S2 |
Product Overview
(E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one (CAS 307342-99-0), with molecular formula C15H16BrN3OS and molecular weight 365.02 g/mol. IUPAC: (5E)-5-[(4-bromophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one.
Chemical Property Profile of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
Property Insights of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
The XLogP value of 2.6668 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one. With a topological polar surface area (TPSA) of 35.91 Ų, (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The CAS number of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is 307342-99-0.
What is the molecular formula of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The molecular formula of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is C15H16BrN3OS.
What is the molecular weight of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The molecular weight of (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is 365.02 g/mol.
Where can I buy (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
You can request a quote for (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-5-(4-bromobenzylidene)-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.