(E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide
TL;DR: (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide (CAS 307323-46-2) is a chemical compound with molecular formula C18H18N4OS and molecular weight 338.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide
Also Known As: (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide, 5-THIOPHEN-2-YL-2H-PYRAZOLE-3-CARBOXYLIC ACID (4-ISOPROPYL-BENZYLIDENE)HYDRAZIDE, N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide, N-{(1E)-2-[4-(methylethyl)phenyl]-1-azavinyl}(3-(2-thienyl)pyrazol-5-yl)carbox amide, N'-[(E)-[4-(PROPAN-2-YL)PHENYL]METHYLIDENE]-3-(THIOPHEN-2-YL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE
| Molecular Formula | C18H18N4OS |
|---|---|
| Molecular Weight | 338.12 g/mol |
| LogP | 4.0255 |
| Topological Polar Surface Area | 70.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 338.12012 |
| Heavy Atoms | 24 |
| Complexity | 832.29816 |
Chemical Identifiers
| CAS Number | 307323-46-2 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)/C=N/NC(=O)C2=NNC(=C2)C3=CC=CS3 |
Product Overview
(E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide (CAS 307323-46-2), with molecular formula C18H18N4OS and molecular weight 338.12 g/mol. IUPAC: N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide.
Chemical Property Profile of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide
Property Insights of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide
The XLogP value of 4.0255 indicates that (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.14 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide?
The CAS number of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide is 307323-46-2.
What is the molecular formula of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide?
The molecular formula of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide is C18H18N4OS.
What is the molecular weight of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide?
The molecular weight of (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide is 338.12 g/mol.
Where can I buy (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide?
You can request a quote for (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(4-isopropylbenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.