(2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one
TL;DR: (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one (CAS 307306-09-8) is a chemical compound with molecular formula C11H12FNO3 and molecular weight 225.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one
Also Known As: J1.361.150E, (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one, (2R,5R)-5-(4-amino-2-fluoro-phenyl)-2-(hydroxymethyl)tetrahydrofuran-3-one, (2R)-2beta-(4-Amino-2-fluorophenyl)-5beta-(hydroxymethyl)-2,3-dihydrofuran-4(5H)-one, (2R,5R)-5-(4-Amino-2-fluorophenyl)dihydro-2-(hydroxymethyl)-3(2H)-furanone
| Molecular Formula | C11H12FNO3 |
|---|---|
| Molecular Weight | 225.08 g/mol |
| LogP | 0.5 |
| Topological Polar Surface Area | 72.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 225.08012 |
| Heavy Atoms | 16 |
| Complexity | 274.0 |
Chemical Identifiers
| CAS Number | 307306-09-8 |
|---|---|
| SMILES | C1[C@@H](O[C@@H](C1=O)CO)C2=C(C=C(C=C2)N)F |
| InChIKey | PBLBYMDQMBUMLZ-GHMZBOCLSA-N |
Product Overview
(2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one (CAS 307306-09-8), with molecular formula C11H12FNO3 and molecular weight 225.08 g/mol. IUPAC: (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one.
Chemical Property Profile of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one
Property Insights of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one
The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one. The TPSA of 72.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one. Following Lipinski's Rule of Five, (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one?
The CAS number of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one is 307306-09-8.
What is the molecular formula of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one?
The molecular formula of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one is C11H12FNO3.
What is the molecular weight of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one?
The molecular weight of (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one is 225.08 g/mol.
Where can I buy (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one?
You can request a quote for (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one?
Yes, KEHONG BIO provides custom synthesis services for (2R,5R)-5-(4-amino-2-fluorophenyl)-2-(hydroxymethyl)oxolan-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.