![6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone structure](/static/products/3069/306978-99-4.webp)
6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone
TL;DR: 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone (CAS 306978-99-4) is a chemical compound with molecular formula C15H7Cl2F3N2O2 and molecular weight 373.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one
Also Known As: 12J-531S, 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone, 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one, 6,8-Dichloro-3-hydroxy-2-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one, 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one
| Molecular Formula | C15H7Cl2F3N2O2 |
|---|---|
| Molecular Weight | 373.98 g/mol |
| LogP | 4.6264 |
| Topological Polar Surface Area | 55.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 373.98367 |
| Heavy Atoms | 24 |
| Complexity | 1015.9974 |
Chemical Identifiers
| CAS Number | 306978-99-4 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)C2=NC3=C(C=C(C=C3Cl)Cl)C(=O)N2O |
Product Overview
6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone (CAS 306978-99-4), with molecular formula C15H7Cl2F3N2O2 and molecular weight 373.98 g/mol. IUPAC: 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one.
Chemical Property Profile of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone
Property Insights of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone
The XLogP value of 4.6264 indicates that 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.12 Ų, 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone?
The CAS number of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone is 306978-99-4.
What is the molecular formula of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone?
The molecular formula of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone is C15H7Cl2F3N2O2.
What is the molecular weight of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone?
The molecular weight of 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone is 373.98 g/mol.
Where can I buy 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone?
You can request a quote for 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone?
Yes, KEHONG BIO provides custom synthesis services for 6,8-dichloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.