12G-905
TL;DR: 12G-905 (CAS 306977-22-0) is a chemical compound with molecular formula C15H17ClF3N3O and molecular weight 347.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridin-4-yl]morpholine
Also Known As: 12G-905, 4-[1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3,6-dihydro-2H-pyridin-4-yl]morpholine, 4-{1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1,2,3,6-tetrahydro-4-pyridinyl}morpholine, 3'-chloro-4-(morpholin-4-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine, 4-(3'-Chloro-5'-(trifluoromethyl)-3,6-dihydro-2H-[1,2'-bipyridin]-4-yl)morpholine
| Molecular Formula | C15H17ClF3N3O |
|---|---|
| Molecular Weight | 347.10 g/mol |
| LogP | 3.18 |
| Topological Polar Surface Area | 28.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 347.10123 |
| Heavy Atoms | 23 |
| Complexity | 600.1202 |
Chemical Identifiers
| CAS Number | 306977-22-0 |
|---|---|
| SMILES | C1CN(CC=C1N2CCOCC2)C3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
12G-905 (CAS 306977-22-0), with molecular formula C15H17ClF3N3O and molecular weight 347.10 g/mol. IUPAC: 4-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridin-4-yl]morpholine.
Chemical Property Profile of 12G-905
Property Insights of 12G-905
The XLogP value of 3.18 indicates that 12G-905 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.6 Ų, 12G-905 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 12G-905 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12G-905?
The CAS number of 12G-905 is 306977-22-0.
What is the molecular formula of 12G-905?
The molecular formula of 12G-905 is C15H17ClF3N3O.
What is the molecular weight of 12G-905?
The molecular weight of 12G-905 is 347.10 g/mol.
Where can I buy 12G-905?
You can request a quote for 12G-905 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12G-905?
Yes, KEHONG BIO provides custom synthesis services for 12G-905 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.