4'-Ethynyl-2'-deoxyadenosine structure

4'-Ethynyl-2'-deoxyadenosine

TL;DR: 4'-Ethynyl-2'-deoxyadenosine (CAS 306305-07-7) is a chemical compound with molecular formula C12H13N5O3 and molecular weight 275.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol

Also Known As: EdAdo, 4'-ethynyl-2'-deoxyadenosine, 4'-C-ethynyl dAdo, 2'-deoxy-4'-ethynyladenosine, 2'-Deoxy-4'-C-ethynyl-Adenosine

CAS: 306305-07-7
Molecular Formula C12H13N5O3
Molecular Weight 275.10 g/mol
LogP -0.6
Topological Polar Surface Area 119.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 7
Rotatable Bonds 3
Exact Mass 275.10184
Heavy Atoms 20
Complexity 427.0

Chemical Identifiers

CAS Number 306305-07-7
SMILES C#C[C@]1([C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)CO
InChIKey HMIGVKANVVLEOA-JOAULVNJSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (17 patents) Pharmaceutical Intermediates (17 patents)

Product Overview

4'-Ethynyl-2'-deoxyadenosine (CAS 306305-07-7), with molecular formula C12H13N5O3 and molecular weight 275.10 g/mol. IUPAC: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4'-Ethynyl-2'-deoxyadenosine

XLogP
-0.6
TPSA (Topological Polar Surface Area)
119.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
7
Rotatable Bonds
3
Heavy Atoms
20
Complexity
427.0
Exact Mass
275.10184
Monoisotopic Mass
275.10184
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4'-Ethynyl-2'-deoxyadenosine

The XLogP value of -0.6 indicates that 4'-Ethynyl-2'-deoxyadenosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4'-Ethynyl-2'-deoxyadenosine. Following Lipinski's Rule of Five, 4'-Ethynyl-2'-deoxyadenosine has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4'-Ethynyl-2'-deoxyadenosine?

The CAS number of 4'-Ethynyl-2'-deoxyadenosine is 306305-07-7.

What is the molecular formula of 4'-Ethynyl-2'-deoxyadenosine?

The molecular formula of 4'-Ethynyl-2'-deoxyadenosine is C12H13N5O3.

What is the molecular weight of 4'-Ethynyl-2'-deoxyadenosine?

The molecular weight of 4'-Ethynyl-2'-deoxyadenosine is 275.10 g/mol.

Where can I buy 4'-Ethynyl-2'-deoxyadenosine?

You can request a quote for 4'-Ethynyl-2'-deoxyadenosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4'-Ethynyl-2'-deoxyadenosine?

Yes, KEHONG BIO provides custom synthesis services for 4'-Ethynyl-2'-deoxyadenosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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