1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
TL;DR: 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol (CAS 305854-49-3) is a chemical compound with molecular formula C20H14F3N3O2 and molecular weight 385.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(2-phenylquinolin-4-yl)methanone
Also Known As: EX-A11587, [5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(2-phenylquinolin-4-yl)methanone, 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol, Methanone, [4,5-dihydro-5-hydroxy-5-(trifluoromethyl)-1H-pyrazol-1-yl](2-phenyl-4-quinolinyl)-
| Molecular Formula | C20H14F3N3O2 |
|---|---|
| Molecular Weight | 385.10 g/mol |
| LogP | 3.9844 |
| Topological Polar Surface Area | 65.79 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 385.10382 |
| Heavy Atoms | 28 |
| Complexity | 1082.9961 |
Chemical Identifiers
| CAS Number | 305854-49-3 |
|---|---|
| SMILES | C1C=NN(C1(C(F)(F)F)O)C(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4 |
Product Overview
1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol (CAS 305854-49-3), with molecular formula C20H14F3N3O2 and molecular weight 385.10 g/mol. IUPAC: [5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(2-phenylquinolin-4-yl)methanone.
Chemical Property Profile of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
Property Insights of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
The XLogP value of 3.9844 indicates that 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.79 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol. Following Lipinski's Rule of Five, 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol?
The CAS number of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol is 305854-49-3.
What is the molecular formula of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol?
The molecular formula of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol is C20H14F3N3O2.
What is the molecular weight of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol?
The molecular weight of 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol is 385.10 g/mol.
Where can I buy 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol?
You can request a quote for 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-phenylquinoline-4-carbonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.