(2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide
TL;DR: (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide (CAS 305375-12-6) is a chemical compound with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-(2-hydroxyphenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: BAS 01370482, (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide, 2-Cyano-N-(2-hydroxy-phenyl)-3-thiophen-2-yl-acrylamide, (E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)acrylamide, (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(2-thienyl)prop-2-enamide
| Molecular Formula | C14H10N2O2S |
|---|---|
| Molecular Weight | 270.05 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 270.0463 |
| Heavy Atoms | 19 |
| Complexity | 413.0 |
Chemical Identifiers
| CAS Number | 305375-12-6 |
|---|---|
| SMILES | C1=CC=C(C(=C1)NC(=O)/C(=C/C2=CC=CS2)/C#N)O |
| InChIKey | HQRHXDNTSYKTLD-CSKARUKUSA-N |
Product Overview
(2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide (CAS 305375-12-6), with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol. IUPAC: (E)-2-cyano-N-(2-hydroxyphenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide
Property Insights of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 3.0 indicates that (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide. Following Lipinski's Rule of Five, (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide is 305375-12-6.
What is the molecular formula of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide is C14H10N2O2S.
What is the molecular weight of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide is 270.05 g/mol.
Where can I buy (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-cyano-N-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.