![1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one structure](/static/products/3053/305372-58-1.webp)
1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one
TL;DR: 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one (CAS 305372-58-1) is a chemical compound with molecular formula C14H13ClN2O2 and molecular weight 276.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(5-chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one
Also Known As: IFLab1_001429, 1-[(5-chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one, AF-399/12854003, 1-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)methyl]pyrrolidin-2-one, 1-[(5-chloro-8-hydroxy-7-quinolyl)methyl]pyrrolidin-2-one
| Molecular Formula | C14H13ClN2O2 |
|---|---|
| Molecular Weight | 276.07 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 53.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 276.06656 |
| Heavy Atoms | 19 |
| Complexity | 352.0 |
Chemical Identifiers
| CAS Number | 305372-58-1 |
|---|---|
| SMILES | C1CC(=O)N(C1)CC2=CC(=C3C=CC=NC3=C2O)Cl |
| InChIKey | YWICHOLVOTVAMW-UHFFFAOYSA-N |
Product Overview
1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one (CAS 305372-58-1), with molecular formula C14H13ClN2O2 and molecular weight 276.07 g/mol. IUPAC: 1-[(5-chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one.
Chemical Property Profile of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one
Property Insights of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one. With a topological polar surface area (TPSA) of 53.4 Ų, 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one?
The CAS number of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one is 305372-58-1.
What is the molecular formula of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one?
The molecular formula of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one is C14H13ClN2O2.
What is the molecular weight of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one?
The molecular weight of 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one is 276.07 g/mol.
Where can I buy 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one?
You can request a quote for 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[(5-Chloro-8-hydroxyquinolin-7-yl)methyl]pyrrolidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.