![N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide structure](/static/products/304/304905-83-7.png)
N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide
TL;DR: N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide (CAS 304905-83-7) is a chemical compound with molecular formula C12H8ClFN2OS and molecular weight 282.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide
Also Known As: N'-[(E)-(2-chloro-6-fluorophenyl)methylidene]thiophene-2-carbohydrazide, N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide, N'-(2-chloro-6-fluorobenzylidene)-2-thiophenecarbohydrazide, (E)-N'-(2-chloro-6-fluorobenzylidene)thiophene-2-carbohydrazide, THIOPHENE-2-CARBOXYLIC ACID (2-CHLORO-6-FLUORO-BENZYLIDENE)-HYDRAZIDE
| Molecular Formula | C12H8ClFN2OS |
|---|---|
| Molecular Weight | 282.00 g/mol |
| LogP | 3.3045 |
| Topological Polar Surface Area | 41.46 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 282.003 |
| Heavy Atoms | 18 |
| Complexity | 563.51825 |
Chemical Identifiers
| CAS Number | 304905-83-7 |
|---|---|
| SMILES | C1=CC(=C(C(=C1)Cl)/C=N/NC(=O)C2=CC=CS2)F |
Product Overview
N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide (CAS 304905-83-7), with molecular formula C12H8ClFN2OS and molecular weight 282.00 g/mol. IUPAC: N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide.
Chemical Property Profile of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide
Property Insights of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide
The XLogP value of 3.3045 indicates that N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.46 Ų, N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide?
The CAS number of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide is 304905-83-7.
What is the molecular formula of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide?
The molecular formula of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide is C12H8ClFN2OS.
What is the molecular weight of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide?
The molecular weight of N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide is 282.00 g/mol.
Where can I buy N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide?
You can request a quote for N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]thiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.