6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol
TL;DR: 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol (CAS 304684-43-3) is a chemical compound with molecular formula C7H4F3N3S and molecular weight 219.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(trifluoromethyl)-2H-[1,2,4]triazolo[4,3-a]pyridine-3-thione
Also Known As: 6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-thiol, 6-(trifluoromethyl)-2H-[1,2,4]triazolo[4,3-a]pyridine-3-thione, 6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridine-3-thiol, 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol, 2H-[1,2,4]Triazolo[4,3-a]pyridine-3-thione, 6-trifluoromethyl-
| Molecular Formula | C7H4F3N3S |
|---|---|
| Molecular Weight | 219.01 g/mol |
| LogP | 1.1 |
| Topological Polar Surface Area | 59.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 219.0078 |
| Heavy Atoms | 14 |
| Complexity | 380.0 |
Chemical Identifiers
| CAS Number | 304684-43-3 |
|---|---|
| SMILES | C1=CC2=NNC(=S)N2C=C1C(F)(F)F |
| InChIKey | KQDBGOYFEMRBJM-UHFFFAOYSA-N |
Product Overview
6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol (CAS 304684-43-3), with molecular formula C7H4F3N3S and molecular weight 219.01 g/mol. IUPAC: 6-(trifluoromethyl)-2H-[1,2,4]triazolo[4,3-a]pyridine-3-thione.
Chemical Property Profile of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol
Property Insights of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol
The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol. With a topological polar surface area (TPSA) of 59.7 Ų, 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol?
The CAS number of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol is 304684-43-3.
What is the molecular formula of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol?
The molecular formula of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol is C7H4F3N3S.
What is the molecular weight of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol?
The molecular weight of 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol is 219.01 g/mol.
Where can I buy 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol?
You can request a quote for 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol?
Yes, KEHONG BIO provides custom synthesis services for 6-(Trifluoromethyl)-(1,2,4)triazolo(4,3-a)pyridine-3-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.