AF-399/12154215 structure

AF-399/12154215

TL;DR: AF-399/12154215 (CAS 304643-36-5) is a chemical compound with molecular formula C25H22ClN3O3 and molecular weight 447.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl]benzo[de]isoquinoline-1,3-dione

Also Known As: AF-399/12154215, F0305-0015, 2-(2-(4-(4-chlorobenzoyl)piperazin-1-yl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, 3-{2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl}-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4-dione, 2-[2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl]benzo[de]isoquinoline-1,3-dione

CAS: 304643-36-5
Molecular Formula C25H22ClN3O3
Molecular Weight 447.13 g/mol
LogP 3.5472
Topological Polar Surface Area 60.93 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 447.13498
Heavy Atoms 32
Complexity 1166.0841

Chemical Identifiers

CAS Number 304643-36-5
SMILES C1CN(CCN1CCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O)C(=O)C5=CC=C(C=C5)Cl

Product Overview

AF-399/12154215 (CAS 304643-36-5), with molecular formula C25H22ClN3O3 and molecular weight 447.13 g/mol. IUPAC: 2-[2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl]benzo[de]isoquinoline-1,3-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/12154215

XLogP
3.5472
TPSA (Topological Polar Surface Area)
60.93
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
32
Complexity
1166.0841
Exact Mass
447.13498
Monoisotopic Mass
447.13498
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/12154215

The XLogP value of 3.5472 indicates that AF-399/12154215 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.93 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/12154215. Following Lipinski's Rule of Five, AF-399/12154215 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/12154215?

The CAS number of AF-399/12154215 is 304643-36-5.

What is the molecular formula of AF-399/12154215?

The molecular formula of AF-399/12154215 is C25H22ClN3O3.

What is the molecular weight of AF-399/12154215?

The molecular weight of AF-399/12154215 is 447.13 g/mol.

Where can I buy AF-399/12154215?

You can request a quote for AF-399/12154215 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/12154215?

Yes, KEHONG BIO provides custom synthesis services for AF-399/12154215 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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