12F-903
TL;DR: 12F-903 (CAS 303998-72-3) is a chemical compound with molecular formula C20H17Cl2F3N4S2 and molecular weight 504.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(4-chlorophenyl)sulfanylmethyl]-2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-1,3-thiazole
Also Known As: 12F-903, 1-(4-{[(4-chlorophenyl)sulfanyl]methyl}-1,3-thiazol-2-yl)-4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine, 4-[(4-chlorophenyl)sulfanylmethyl]-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-1,3-thiazole, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(4-{[(4-chlorophenyl)sulfanyl]methyl}-1,3-thiazol-2-yl)piperazine, 1-(4-([(4-CHLOROPHENYL)SULFANYL]METHYL)-1,3-THIAZOL-2-YL)-4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINE
| Molecular Formula | C20H17Cl2F3N4S2 |
|---|---|
| Molecular Weight | 504.02 g/mol |
| LogP | 6.4826 |
| Topological Polar Surface Area | 32.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 504.02237 |
| Heavy Atoms | 31 |
| Complexity | 1035.6494 |
Chemical Identifiers
| CAS Number | 303998-72-3 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=N2)C(F)(F)F)Cl)C3=NC(=CS3)CSC4=CC=C(C=C4)Cl |
Product Overview
12F-903 (CAS 303998-72-3), with molecular formula C20H17Cl2F3N4S2 and molecular weight 504.02 g/mol. IUPAC: 4-[(4-chlorophenyl)sulfanylmethyl]-2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-1,3-thiazole.
Chemical Property Profile of 12F-903
Property Insights of 12F-903
The XLogP value of 6.4826 indicates that 12F-903 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.26 Ų, 12F-903 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 12F-903 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12F-903?
The CAS number of 12F-903 is 303998-72-3.
What is the molecular formula of 12F-903?
The molecular formula of 12F-903 is C20H17Cl2F3N4S2.
What is the molecular weight of 12F-903?
The molecular weight of 12F-903 is 504.02 g/mol.
Where can I buy 12F-903?
You can request a quote for 12F-903 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12F-903?
Yes, KEHONG BIO provides custom synthesis services for 12F-903 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.