12F-399S structure

12F-399S

TL;DR: 12F-399S (CAS 303998-52-9) is a chemical compound with molecular formula C18H10Cl2F5N3OS and molecular weight 480.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(3,4-dichlorophenyl)sulfanyl-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide

Also Known As: 12F-399S, 5-[(3,4-dichlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide, 5-(3,4-dichlorophenyl)sulfanyl-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide, 5-[(3,4-dichlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide

CAS: 303998-52-9
Molecular Formula C18H10Cl2F5N3OS
Molecular Weight 480.98 g/mol
LogP 6.4274
Topological Polar Surface Area 46.92 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 480.9842
Heavy Atoms 30
Complexity 1133.7401

Chemical Identifiers

CAS Number 303998-52-9
SMILES CN1C(=C(C(=N1)C(F)(F)F)C(=O)NC2=C(C=C(C=C2)F)F)SC3=CC(=C(C=C3)Cl)Cl

Product Overview

12F-399S (CAS 303998-52-9), with molecular formula C18H10Cl2F5N3OS and molecular weight 480.98 g/mol. IUPAC: 5-(3,4-dichlorophenyl)sulfanyl-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 12F-399S

XLogP
6.4274
TPSA (Topological Polar Surface Area)
46.92
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
30
Complexity
1133.7401
Exact Mass
480.9842
Monoisotopic Mass
480.9842
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 12F-399S

The XLogP value of 6.4274 indicates that 12F-399S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.92 Ų, 12F-399S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 12F-399S has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 12F-399S?

The CAS number of 12F-399S is 303998-52-9.

What is the molecular formula of 12F-399S?

The molecular formula of 12F-399S is C18H10Cl2F5N3OS.

What is the molecular weight of 12F-399S?

The molecular weight of 12F-399S is 480.98 g/mol.

Where can I buy 12F-399S?

You can request a quote for 12F-399S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 12F-399S?

Yes, KEHONG BIO provides custom synthesis services for 12F-399S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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