![4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine structure](/static/products/3039/303997-62-8.webp)
4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine
TL;DR: 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine (CAS 303997-62-8) is a chemical compound with molecular formula C12H8ClF3N4 and molecular weight 300.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethenyl]pyrimidin-2-amine
Also Known As: 4-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine, 4-[2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]ethenyl]-2-pyrimidinamine, 4-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]pyrimidin-2-amine, 4-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]vinyl}-2-pyrimidinamine
| Molecular Formula | C12H8ClF3N4 |
|---|---|
| Molecular Weight | 300.04 g/mol |
| LogP | 3.2964 |
| Topological Polar Surface Area | 64.69 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 300.03897 |
| Heavy Atoms | 20 |
| Complexity | 655.391 |
Chemical Identifiers
| CAS Number | 303997-62-8 |
|---|---|
| SMILES | C1=CN=C(N=C1C=CC2=C(C=C(C=N2)C(F)(F)F)Cl)N |
Product Overview
4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine (CAS 303997-62-8), with molecular formula C12H8ClF3N4 and molecular weight 300.04 g/mol. IUPAC: 4-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethenyl]pyrimidin-2-amine.
Chemical Property Profile of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine
Property Insights of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine
The XLogP value of 3.2964 indicates that 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.69 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine. Following Lipinski's Rule of Five, 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine?
The CAS number of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine is 303997-62-8.
What is the molecular formula of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine?
The molecular formula of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine is C12H8ClF3N4.
What is the molecular weight of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine?
The molecular weight of 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine is 300.04 g/mol.
Where can I buy 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine?
You can request a quote for 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl}pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.