11H-053
TL;DR: 11H-053 (CAS 303152-01-4) is a chemical compound with molecular formula C18H9Cl2F3N4 and molecular weight 408.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-chlorophenyl)-1-(6-chloro-2-pyridinyl)-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine
Also Known As: 11H-053, 3-(4-chlorophenyl)-1-(6-chloro-2-pyridinyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine, 3-(4-chlorophenyl)-1-(6-chloropyridin-2-yl)-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine, 2-chloro-6-[3-(4-chlorophenyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridin-1-yl]pyridine
| Molecular Formula | C18H9Cl2F3N4 |
|---|---|
| Molecular Weight | 408.02 g/mol |
| LogP | 5.8081 |
| Topological Polar Surface Area | 43.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 408.01562 |
| Heavy Atoms | 27 |
| Complexity | 1137.7633 |
Chemical Identifiers
| CAS Number | 303152-01-4 |
|---|---|
| SMILES | C1=CC(=NC(=C1)Cl)N2C3=C(C(=N2)C4=CC=C(C=C4)Cl)N=CC(=C3)C(F)(F)F |
Product Overview
11H-053 (CAS 303152-01-4), with molecular formula C18H9Cl2F3N4 and molecular weight 408.02 g/mol. IUPAC: 3-(4-chlorophenyl)-1-(6-chloro-2-pyridinyl)-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine.
Chemical Property Profile of 11H-053
Property Insights of 11H-053
The XLogP value of 5.8081 indicates that 11H-053 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.6 Ų, 11H-053 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 11H-053 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11H-053?
The CAS number of 11H-053 is 303152-01-4.
What is the molecular formula of 11H-053?
The molecular formula of 11H-053 is C18H9Cl2F3N4.
What is the molecular weight of 11H-053?
The molecular weight of 11H-053 is 408.02 g/mol.
Where can I buy 11H-053?
You can request a quote for 11H-053 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11H-053?
Yes, KEHONG BIO provides custom synthesis services for 11H-053 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.