![[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone structure](/static/products/3031/303151-57-7.webp)
[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone
TL;DR: [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone (CAS 303151-57-7) is a chemical compound with molecular formula C23H22ClFN4O3 and molecular weight 456.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]-[8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]decan-4-yl]methanone
Also Known As: [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone, [3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]-[8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]decan-4-yl]methanone, [3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]-[8-(6-fluoropyridin-2-yl)-4-oxa-1,8-diazaspiro[4.5]decan-1-yl]methanone, 4-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]decane
| Molecular Formula | C23H22ClFN4O3 |
|---|---|
| Molecular Weight | 456.14 g/mol |
| LogP | 4.30662 |
| Topological Polar Surface Area | 71.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 456.13644 |
| Heavy Atoms | 32 |
| Complexity | 1159.6482 |
Chemical Identifiers
| CAS Number | 303151-57-7 |
|---|---|
| SMILES | CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)N3CCOC34CCN(CC4)C5=NC(=CC=C5)F |
Product Overview
[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone (CAS 303151-57-7), with molecular formula C23H22ClFN4O3 and molecular weight 456.14 g/mol. IUPAC: [3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]-[8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]decan-4-yl]methanone.
Chemical Property Profile of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone
Property Insights of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone
The XLogP value of 4.30662 indicates that [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.7 Ų falls within the moderate polarity range, balancing permeability and solubility for [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone. Following Lipinski's Rule of Five, [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone?
The CAS number of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone is 303151-57-7.
What is the molecular formula of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone?
The molecular formula of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone is C23H22ClFN4O3.
What is the molecular weight of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone?
The molecular weight of [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone is 456.14 g/mol.
Where can I buy [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone?
You can request a quote for [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [3-(2-chlorophenyl)-5-methyl-4-isoxazolyl][8-(6-fluoro-2-pyridinyl)-1-oxa-4,8-diazaspiro[4.5]dec-4-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.