11F-021
TL;DR: 11F-021 (CAS 303147-90-2) is a chemical compound with molecular formula C18H14ClF3N4O2S and molecular weight 442.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-(3-phenylmethoxythiophen-2-yl)urea
Also Known As: 11F-021, N-[3-(benzyloxy)-2-thienyl]-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-hydrazinecarboxamide, 1-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-3-(3-phenylmethoxythiophen-2-yl)urea, 3-[3-(benzyloxy)thiophen-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}urea, 3-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-1-(3-phenylmethoxythiophen-2-yl)urea
| Molecular Formula | C18H14ClF3N4O2S |
|---|---|
| Molecular Weight | 442.05 g/mol |
| LogP | 5.5429 |
| Topological Polar Surface Area | 75.28 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 442.04782 |
| Heavy Atoms | 29 |
| Complexity | 982.7376 |
Chemical Identifiers
| CAS Number | 303147-90-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)COC2=C(SC=C2)NC(=O)NNC3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
11F-021 (CAS 303147-90-2), with molecular formula C18H14ClF3N4O2S and molecular weight 442.05 g/mol. IUPAC: 1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-(3-phenylmethoxythiophen-2-yl)urea.
Chemical Property Profile of 11F-021
Property Insights of 11F-021
The XLogP value of 5.5429 indicates that 11F-021 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.28 Ų falls within the moderate polarity range, balancing permeability and solubility for 11F-021. Following Lipinski's Rule of Five, 11F-021 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11F-021?
The CAS number of 11F-021 is 303147-90-2.
What is the molecular formula of 11F-021?
The molecular formula of 11F-021 is C18H14ClF3N4O2S.
What is the molecular weight of 11F-021?
The molecular weight of 11F-021 is 442.05 g/mol.
Where can I buy 11F-021?
You can request a quote for 11F-021 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11F-021?
Yes, KEHONG BIO provides custom synthesis services for 11F-021 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.