3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
TL;DR: 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 303106-96-9) is a chemical compound with molecular formula C18H17ClN4O4S and molecular weight 420.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5-chlorothiophen-2-yl)-N-[(E)-(2,4,5-trimethoxyphenyl)methylideneamino]-1H-pyrazole-3-carboxamide
Also Known As: BAS 01859536, 5-(5-Chlorothiophen-2-yl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-3-carbohydrazide, 3-(5-CL-2-THIENYL)-N'-(2,4,5-TRIMETHOXYBENZYLIDENE)-1H-PYRAZOLE-5-CARBOHYDRAZIDE, 3-(5-chlorothiophen-2-yl)-N'-[(E)-(2,4,5-trimethoxyphenyl)methylidene]-1H-pyrazole-5-carbohydrazide, (E)-3-(5-chlorothiophen-2-yl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
| Molecular Formula | C18H17ClN4O4S |
|---|---|
| Molecular Weight | 420.07 g/mol |
| LogP | 3.5813 |
| Topological Polar Surface Area | 97.83 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 420.06592 |
| Heavy Atoms | 28 |
| Complexity | 1014.9368 |
Chemical Identifiers
| CAS Number | 303106-96-9 |
|---|---|
| SMILES | COC1=CC(=C(C=C1/C=N/NC(=O)C2=NNC(=C2)C3=CC=C(S3)Cl)OC)OC |
Product Overview
3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 303106-96-9), with molecular formula C18H17ClN4O4S and molecular weight 420.07 g/mol. IUPAC: 5-(5-chlorothiophen-2-yl)-N-[(E)-(2,4,5-trimethoxyphenyl)methylideneamino]-1H-pyrazole-3-carboxamide.
Chemical Property Profile of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
Property Insights of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
The XLogP value of 3.5813 indicates that 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The CAS number of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide is 303106-96-9.
What is the molecular formula of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular formula of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide is C18H17ClN4O4S.
What is the molecular weight of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular weight of 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide is 420.07 g/mol.
Where can I buy 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
You can request a quote for 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-CL-2-Thienyl)-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.