N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide
TL;DR: N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide (CAS 303091-36-3) is a chemical compound with molecular formula C20H18F7N3O and molecular weight 449.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,5-bis(trifluoromethyl)phenyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
Also Known As: N-[3,5-bis(trifluoromethyl)phenyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide, N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide, N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-[4-(4-fluorophenyl)-1-piperazinyl]acetamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-[4-(4-fluorophenyl)piperazino]acetamide
| Molecular Formula | C20H18F7N3O |
|---|---|
| Molecular Weight | 449.13 g/mol |
| LogP | 4.624 |
| Topological Polar Surface Area | 35.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 449.13382 |
| Heavy Atoms | 31 |
| Complexity | 885.6012 |
Chemical Identifiers
| CAS Number | 303091-36-3 |
|---|---|
| SMILES | C1CN(CCN1CC(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C3=CC=C(C=C3)F |
Product Overview
N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide (CAS 303091-36-3), with molecular formula C20H18F7N3O and molecular weight 449.13 g/mol. IUPAC: N-[3,5-bis(trifluoromethyl)phenyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide.
Chemical Property Profile of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide
Property Insights of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide
The XLogP value of 4.624 indicates that N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.58 Ų, N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide?
The CAS number of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide is 303091-36-3.
What is the molecular formula of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide?
The molecular formula of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide is C20H18F7N3O.
What is the molecular weight of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide?
The molecular weight of N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide is 449.13 g/mol.
Where can I buy N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide?
You can request a quote for N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3,5-Bis(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)-1-piperazinyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.