氯米帕明
TL;DR: 氯米帕明 (CAS 303-49-1) is a chemical compound with molecular formula C19H23ClN2 and molecular weight 314.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氯米帕明
3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Also Known As: clomipramine, Chlorimipramine, Monochlorimipramine, 3-Chloroimipramine, Hydiphen
| Molecular Formula | C19H23ClN2 |
|---|---|
| Molecular Weight | 314.15 g/mol |
| LogP | 5.2 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 314.15497 |
| Heavy Atoms | 22 |
| Complexity | 346.0 |
| Melting Point | 191.5-192 |
| Boiling Point | 160-170 °C at 3.00E-01 mm Hg |
| Solubility | 0.294 |
Chemical Identifiers
| CAS Number | 303-49-1 |
|---|---|
| SMILES | CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl |
| InChIKey | GDLIGKIOYRNHDA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
氯米帕明 (CAS 303-49-1), with molecular formula C19H23ClN2 and molecular weight 314.15 g/mol. IUPAC: 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine.
Chemical Property Profile of 氯米帕明
Property Insights of 氯米帕明
The XLogP value of 5.2 indicates that 氯米帕明 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, 氯米帕明 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氯米帕明 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氯米帕明?
The CAS number of 氯米帕明 is 303-49-1.
What is the molecular formula of 氯米帕明?
The molecular formula of 氯米帕明 is C19H23ClN2.
What is the molecular weight of 氯米帕明?
The molecular weight of 氯米帕明 is 314.15 g/mol.
Where can I buy 氯米帕明?
You can request a quote for 氯米帕明 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氯米帕明?
Yes, KEHONG BIO provides custom synthesis services for 氯米帕明 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.