Norclomipramine
TL;DR: Norclomipramine (CAS 303-48-0) is a chemical compound with molecular formula C18H21ClN2 and molecular weight 300.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
Also Known As: Desmethylclomipramine, Norclomipramine, chlordesipramine, Norchlorimipramine, Demethylchlorimipramine
| Molecular Formula | C18H21ClN2 |
|---|---|
| Molecular Weight | 300.14 g/mol |
| LogP | 4.7 |
| Topological Polar Surface Area | 15.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 300.1393 |
| Heavy Atoms | 21 |
| Complexity | 322.0 |
Chemical Identifiers
| CAS Number | 303-48-0 |
|---|---|
| SMILES | CNCCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl |
| InChIKey | VPIXQGUBUKFLRF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Norclomipramine (CAS 303-48-0), with molecular formula C18H21ClN2 and molecular weight 300.14 g/mol. IUPAC: 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine.
Chemical Property Profile of Norclomipramine
Property Insights of Norclomipramine
The XLogP value of 4.7 indicates that Norclomipramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.3 Ų, Norclomipramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Norclomipramine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Norclomipramine?
The CAS number of Norclomipramine is 303-48-0.
What is the molecular formula of Norclomipramine?
The molecular formula of Norclomipramine is C18H21ClN2.
What is the molecular weight of Norclomipramine?
The molecular weight of Norclomipramine is 300.14 g/mol.
Where can I buy Norclomipramine?
You can request a quote for Norclomipramine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Norclomipramine?
Yes, KEHONG BIO provides custom synthesis services for Norclomipramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.