F0446-0030
TL;DR: F0446-0030 (CAS 302934-91-4) is a chemical compound with molecular formula C20H19ClN2O3 and molecular weight 370.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 6-(2-chlorophenyl)-4-methyl-2-oxo-3-phenyl-1,6-dihydropyrimidine-5-carboxylate
Also Known As: F0446-0030, ethyl 4-(2-chlorophenyl)-6-methyl-2-oxo-1-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate, ethyl 6-(2-chlorophenyl)-4-methyl-2-oxo-3-phenyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-(2-chlorophenyl)-4-methyl-2-oxo-3-phenyl-1,3,6-trihydropyrimidine-5-ca rboxylate, ethyl 4-(o-chlorophenyl)-6-methyl-2-oxo-1-phenyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
| Molecular Formula | C20H19ClN2O3 |
|---|---|
| Molecular Weight | 370.11 g/mol |
| LogP | 4.448 |
| Topological Polar Surface Area | 58.64 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 370.10843 |
| Heavy Atoms | 26 |
| Complexity | 864.3698 |
Chemical Identifiers
| CAS Number | 302934-91-4 |
|---|---|
| SMILES | CCOC(=O)C1=C(N(C(=O)NC1C2=CC=CC=C2Cl)C3=CC=CC=C3)C |
Product Overview
F0446-0030 (CAS 302934-91-4), with molecular formula C20H19ClN2O3 and molecular weight 370.11 g/mol. IUPAC: ethyl 6-(2-chlorophenyl)-4-methyl-2-oxo-3-phenyl-1,6-dihydropyrimidine-5-carboxylate.
Chemical Property Profile of F0446-0030
Property Insights of F0446-0030
The XLogP value of 4.448 indicates that F0446-0030 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.64 Ų, F0446-0030 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0446-0030 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0446-0030?
The CAS number of F0446-0030 is 302934-91-4.
What is the molecular formula of F0446-0030?
The molecular formula of F0446-0030 is C20H19ClN2O3.
What is the molecular weight of F0446-0030?
The molecular weight of F0446-0030 is 370.11 g/mol.
Where can I buy F0446-0030?
You can request a quote for F0446-0030 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0446-0030?
Yes, KEHONG BIO provides custom synthesis services for F0446-0030 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.