3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide
TL;DR: 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302918-77-0) is a chemical compound with molecular formula C16H13ClN4O2S and molecular weight 360.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5-chlorothiophen-2-yl)-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-pyrazole-3-carboxamide
Also Known As: BAS 01859556, 3-(5-Chlorothiophen-2-yl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide, 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide, 3-(5-chloro-2-thienyl)-N'-[(E)-(2-methoxyphenyl)methylidene]-1H-pyrazole-5-carbohydrazide, N-[(1E)-2-(2-methoxyphenyl)-1-azavinyl][3-(5-chloro(2-thienyl))pyrazol-5-yl]ca rboxamide
| Molecular Formula | C16H13ClN4O2S |
|---|---|
| Molecular Weight | 360.04 g/mol |
| LogP | 3.5641 |
| Topological Polar Surface Area | 79.37 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 360.04477 |
| Heavy Atoms | 24 |
| Complexity | 887.5971 |
Chemical Identifiers
| CAS Number | 302918-77-0 |
|---|---|
| SMILES | COC1=CC=CC=C1/C=N/NC(=O)C2=NNC(=C2)C3=CC=C(S3)Cl |
Product Overview
3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302918-77-0), with molecular formula C16H13ClN4O2S and molecular weight 360.04 g/mol. IUPAC: 5-(5-chlorothiophen-2-yl)-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-pyrazole-3-carboxamide.
Chemical Property Profile of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide
Property Insights of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide
The XLogP value of 3.5641 indicates that 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.37 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The CAS number of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide is 302918-77-0.
What is the molecular formula of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular formula of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide is C16H13ClN4O2S.
What is the molecular weight of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular weight of 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide is 360.04 g/mol.
Where can I buy 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
You can request a quote for 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-Chloro-2-thienyl)-N'-(2-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.