3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide
TL;DR: 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302918-76-9) is a chemical compound with molecular formula C19H20ClN5OS and molecular weight 401.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5-chlorothiophen-2-yl)-N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-1H-pyrazole-3-carboxamide
Also Known As: BAS 01859554, 5-(5-Chlorothiophen-2-yl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-3-carbohydrazide, 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide, 3-(5-chloro-2-thienyl)-N'-{(E)-[4-(diethylamino)phenyl]methylidene}-1H-pyrazole-5-carbohydrazide, 3-(5-CHLOROTHIOPHEN-2-YL)-N'-[(E)-[4-(DIETHYLAMINO)PHENYL]METHYLIDENE]-1H-PYRAZOLE-5-CARBOHYDRAZIDE
| Molecular Formula | C19H20ClN5OS |
|---|---|
| Molecular Weight | 401.11 g/mol |
| LogP | 4.4017 |
| Topological Polar Surface Area | 73.38 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 401.1077 |
| Heavy Atoms | 27 |
| Complexity | 927.7404 |
Chemical Identifiers
| CAS Number | 302918-76-9 |
|---|---|
| SMILES | CCN(CC)C1=CC=C(C=C1)/C=N/NC(=O)C2=NNC(=C2)C3=CC=C(S3)Cl |
Product Overview
3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302918-76-9), with molecular formula C19H20ClN5OS and molecular weight 401.11 g/mol. IUPAC: 5-(5-chlorothiophen-2-yl)-N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-1H-pyrazole-3-carboxamide.
Chemical Property Profile of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide
Property Insights of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide
The XLogP value of 4.4017 indicates that 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.38 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide?
The CAS number of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide is 302918-76-9.
What is the molecular formula of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular formula of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide is C19H20ClN5OS.
What is the molecular weight of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide?
The molecular weight of 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide is 401.11 g/mol.
Where can I buy 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide?
You can request a quote for 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-CL-2-Thienyl)-N'-(4-(diethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.