N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide
TL;DR: N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide (CAS 302552-73-4) is a chemical compound with molecular formula C13H10F2N2O2S2 and molecular weight 328.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[4-(difluoromethoxy)phenyl]carbamothioyl]thiophene-2-carboxamide
Also Known As: N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide, F1065-0376, N-[[4-(difluoromethoxy)phenyl]carbamothioyl]thiophene-2-carboxamide, 1-[4-(DIFLUOROMETHOXY)PHENYL]-3-(THIOPHENE-2-CARBONYL)THIOUREA
| Molecular Formula | C13H10F2N2O2S2 |
|---|---|
| Molecular Weight | 328.02 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 111.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 328.01517 |
| Heavy Atoms | 21 |
| Complexity | 377.0 |
Chemical Identifiers
| CAS Number | 302552-73-4 |
|---|---|
| SMILES | C1=CSC(=C1)C(=O)NC(=S)NC2=CC=C(C=C2)OC(F)F |
| InChIKey | NXHQWOYHCGDWON-UHFFFAOYSA-N |
Product Overview
N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide (CAS 302552-73-4), with molecular formula C13H10F2N2O2S2 and molecular weight 328.02 g/mol. IUPAC: N-[[4-(difluoromethoxy)phenyl]carbamothioyl]thiophene-2-carboxamide.
Chemical Property Profile of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide
Property Insights of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide
The XLogP value of 4.5 indicates that N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 111.0 Ų falls within the moderate polarity range, balancing permeability and solubility for N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide. Following Lipinski's Rule of Five, N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide?
The CAS number of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide is 302552-73-4.
What is the molecular formula of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide?
The molecular formula of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide is C13H10F2N2O2S2.
What is the molecular weight of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide?
The molecular weight of N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide is 328.02 g/mol.
Where can I buy N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide?
You can request a quote for N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-((4-(difluoromethoxy)phenyl)carbamothioyl)thiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.