(8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate structure

(8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate

TL;DR: (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate (CAS 302323-33-7) is a chemical compound with molecular formula C21H21N5O3 and molecular weight 391.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate

Also Known As: (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate, tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate

CAS: 302323-33-7
Molecular Formula C21H21N5O3
Molecular Weight 391.16 g/mol
LogP 2.94004
Topological Polar Surface Area 140.07 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 1
Exact Mass 391.16443
Heavy Atoms 29
Complexity 994.6871

Chemical Identifiers

CAS Number 302323-33-7
SMILES CC(C)(C)OC(=O)N1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=COC=C3

Product Overview

(8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate (CAS 302323-33-7), with molecular formula C21H21N5O3 and molecular weight 391.16 g/mol. IUPAC: tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate

XLogP
2.94004
TPSA (Topological Polar Surface Area)
140.07
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
1
Heavy Atoms
29
Complexity
994.6871
Exact Mass
391.16443
Monoisotopic Mass
391.16443
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate

The XLogP value of 2.94004 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate. The TPSA of 140.07 Ų indicates high polarity, suggesting (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate?

The CAS number of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate is 302323-33-7.

What is the molecular formula of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate?

The molecular formula of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate is C21H21N5O3.

What is the molecular weight of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate?

The molecular weight of (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate is 391.16 g/mol.

Where can I buy (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate?

You can request a quote for (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(furan-3-yl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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