![(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one structure](/static/products/300/300818-33-1.png)
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one
概要：(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one（CAS 300818-33-1）是一种化学化合物，分子式为C15H12F3N3O2S，分子量为355.06 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1H-pyrazol-3-yl]benzene-1,3-diol
又称：(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one, (4Z)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one, 3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one, 5-methyl-4-(4-(2-methylthiazol-4-yl)-5-(trifluoromethyl)-1H-pyrazol-3-yl)benzene-1,3-diol, 5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzene-1,3-diol
| 分子式 | C15H12F3N3O2S |
|---|---|
| 分子量 | 355.06 g/mol |
| LogP | 4.24704 |
| 拓扑极性表面积 | 82.03 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 5 |
| 可旋转键数 | 2 |
| 精确质量 | 355.06024 |
| 重原子数 | 24 |
| 复杂度 | 892.06793 |
化学标识符
| CAS 编号 | 300818-33-1 |
|---|---|
| SMILES | CC1=CC(=CC(=C1C2=NNC(=C2C3=CSC(=N3)C)C(F)(F)F)O)O |
产品概述
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one（CAS 300818-33-1），分子式为C15H12F3N3O2S，分子量为355.06 g/mol。IUPAC名：5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1H-pyrazol-3-yl]benzene-1,3-diol。
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one化学性质概览
属性洞察：(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的XLogP值为4.24704，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为82.03 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one有3个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的CAS号是多少？
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的CAS号为300818-33-1。
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的分子式是什么？
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的分子式为C15H12F3N3O2S。
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的分子量是多少？
(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的分子量为355.06 g/mol。
在哪里可以购买(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one？
您可以直接向科弘生物询价(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one的定制合成服务？
是的，科弘生物提供(4E)-3-hydroxy-5-methyl-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。