(E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide
TL;DR: (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide (CAS 300813-97-2) is a chemical compound with molecular formula C16H11BrN2OS and molecular weight 357.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide
Also Known As: BIM-0006018.P001, (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide, (E)-3-(4-bromothiophen-2-yl)-N-(quinolin-5-yl)acrylamide, (2E)-3-(4-bromo(2-thienyl))-N-(5-quinolyl)prop-2-enamide, (2E)-3-(4-bromothiophen-2-yl)-N-(quinolin-5-yl)prop-2-enamide
| Molecular Formula | C16H11BrN2OS |
|---|---|
| Molecular Weight | 357.98 g/mol |
| LogP | 4.7107 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 357.97754 |
| Heavy Atoms | 21 |
| Complexity | 820.51483 |
Chemical Identifiers
| CAS Number | 300813-97-2 |
|---|---|
| SMILES | C1=CC2=C(C=CC=N2)C(=C1)NC(=O)/C=C/C3=CC(=CS3)Br |
Product Overview
(E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide (CAS 300813-97-2), with molecular formula C16H11BrN2OS and molecular weight 357.98 g/mol. IUPAC: (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide.
Chemical Property Profile of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide
Property Insights of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide
The XLogP value of 4.7107 indicates that (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide?
The CAS number of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide is 300813-97-2.
What is the molecular formula of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide?
The molecular formula of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide is C16H11BrN2OS.
What is the molecular weight of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide?
The molecular weight of (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide is 357.98 g/mol.
Where can I buy (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide?
You can request a quote for (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(4-bromothiophen-2-yl)-N-quinolin-5-ylprop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.