Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate structure

Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate

TL;DR: Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate (CAS 3005-63-8) is a chemical compound with molecular formula C18H23NO6 and molecular weight 349.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate

Also Known As: diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate, diethyl 1-acetyl-5-hydroxy-3-phenyl-2,2-pyrrolidinedicarboxylate, 1-Acetyl-3-phenyl-5-hydroxypyrrolidine-2,2-dicarboxylic acid diethyl ester, 2,2-Diethyl 1-acetyl-5-hydroxy-3-phenyl-2,2-pyrrolidinedicarboxylate, 2,2-DIETHYL 1-ACETYL-5-HYDROXY-3-PHENYLPYRROLIDINE-2,2-DICARBOXYLATE

CAS: 3005-63-8
Molecular Formula C18H23NO6
Molecular Weight 349.15 g/mol
LogP 2.2
Topological Polar Surface Area 93.1 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 7
Exact Mass 349.15253
Heavy Atoms 25
Complexity 496.0

Chemical Identifiers

CAS Number 3005-63-8
SMILES CCOC(=O)C1(C(CC(N1C(=O)C)O)C2=CC=CC=C2)C(=O)OCC
InChIKey QNERVFMVXCWNMB-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (3 patents) Organic Building Blocks (6 patents) Organometallic Reagents (9 patents) Peptides & Amino Acids (2 patents) Pharmaceutical Intermediates (29 patents)

Product Overview

Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate (CAS 3005-63-8), with molecular formula C18H23NO6 and molecular weight 349.15 g/mol. IUPAC: diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate

XLogP
2.2
TPSA (Topological Polar Surface Area)
93.1
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
7
Heavy Atoms
25
Complexity
496.0
Exact Mass
349.15253
Monoisotopic Mass
349.15253
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate

The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate. The TPSA of 93.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate. Following Lipinski's Rule of Five, Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate?

The CAS number of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate is 3005-63-8.

What is the molecular formula of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate?

The molecular formula of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate is C18H23NO6.

What is the molecular weight of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate?

The molecular weight of Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate is 349.15 g/mol.

Where can I buy Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate?

You can request a quote for Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate?

Yes, KEHONG BIO provides custom synthesis services for Diethyl 1-acetyl-5-hydroxy-3-phenylpyrrolidine-2,2-dicarboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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