![(E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one structure](/static/products/2999/299934-74-0.webp)
(E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one
TL;DR: (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one (CAS 299934-74-0) is a chemical compound with molecular formula C24H26N6OS and molecular weight 446.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(1,3-benzothiazol-2-yl)-4-[C-methyl-N-(2-piperazin-1-ylethyl)carbonimidoyl]-5-phenyl-1H-pyrazol-3-one
Also Known As: (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one, 2-(1,3-benzothiazol-2-yl)-5-phenyl-4-{(1E)-N-[2-(piperazin-1-yl)ethyl]ethanimidoyl}-1,2-dihydro-3H-pyrazol-3-one, 2-benzothiazol-2-yl-5-phenyl-4-[1-(2-piperazin-1-ylethylamino)ethylidene]pyrazol-3-one, (4Z)-2-(1,3-benzothiazol-2-yl)-5-phenyl-4-(1-{[2-(piperazin-1-yl)ethyl]amino}ethylidene)-2,4-dihydro-3H-pyrazol-3-one, (4Z)-2-(1,3-benzothiazol-2-yl)-5-phenyl-4-[1-(2-piperazin-1-ylethylamino)ethylidene]pyrazol-3-one
| Molecular Formula | C24H26N6OS |
|---|---|
| Molecular Weight | 446.19 g/mol |
| LogP | 3.1565 |
| Topological Polar Surface Area | 78.31 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 446.18887 |
| Heavy Atoms | 32 |
| Complexity | 1264.0306 |
Chemical Identifiers
| CAS Number | 299934-74-0 |
|---|---|
| SMILES | CC(=NCCN1CCNCC1)C2=C(NN(C2=O)C3=NC4=CC=CC=C4S3)C5=CC=CC=C5 |
Product Overview
(E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one (CAS 299934-74-0), with molecular formula C24H26N6OS and molecular weight 446.19 g/mol. IUPAC: 2-(1,3-benzothiazol-2-yl)-4-[C-methyl-N-(2-piperazin-1-ylethyl)carbonimidoyl]-5-phenyl-1H-pyrazol-3-one.
Chemical Property Profile of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one
Property Insights of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one
The XLogP value of 3.1565 indicates that (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.31 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one. Following Lipinski's Rule of Five, (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one?
The CAS number of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one is 299934-74-0.
What is the molecular formula of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one?
The molecular formula of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one is C24H26N6OS.
What is the molecular weight of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one?
The molecular weight of (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one is 446.19 g/mol.
Where can I buy (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one?
You can request a quote for (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-(benzo[d]thiazol-2-yl)-3-phenyl-4-(1-((2-(piperazin-1-yl)ethyl)amino)ethylidene)-1H-pyrazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.