Erlotinib Impurity 14
TL;DR: Erlotinib Impurity 14 (CAS 299912-60-0) is a chemical compound with molecular formula C25H29N3O5 and molecular weight 451.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl]-2-methylbut-3-yn-2-ol
Also Known As: Erlotinib Impurity 14, Erlotinib Impurity 77, 4-(3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbut-3-yn-2-ol, 4-[3-[[6,7-bis(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-2-methyl-3-butyn-2-ol, 4-[3-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl]-2-methyl-but-3-yn-2-ol
| Molecular Formula | C25H29N3O5 |
|---|---|
| Molecular Weight | 451.21 g/mol |
| LogP | 3.5462 |
| Topological Polar Surface Area | 94.96 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 10 |
| Exact Mass | 451.21072 |
| Heavy Atoms | 33 |
| Complexity | 1132.3162 |
Chemical Identifiers
| CAS Number | 299912-60-0 |
|---|---|
| SMILES | CC(C)(C#CC1=CC(=CC=C1)NC2=NC=NC3=CC(=C(C=C32)OCCOC)OCCOC)O |
Product Overview
Erlotinib Impurity 14 (CAS 299912-60-0), with molecular formula C25H29N3O5 and molecular weight 451.21 g/mol. IUPAC: 4-[3-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl]-2-methylbut-3-yn-2-ol.
Chemical Property Profile of Erlotinib Impurity 14
Property Insights of Erlotinib Impurity 14
The XLogP value of 3.5462 indicates that Erlotinib Impurity 14 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.96 Ų falls within the moderate polarity range, balancing permeability and solubility for Erlotinib Impurity 14. Following Lipinski's Rule of Five, Erlotinib Impurity 14 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Erlotinib Impurity 14?
The CAS number of Erlotinib Impurity 14 is 299912-60-0.
What is the molecular formula of Erlotinib Impurity 14?
The molecular formula of Erlotinib Impurity 14 is C25H29N3O5.
What is the molecular weight of Erlotinib Impurity 14?
The molecular weight of Erlotinib Impurity 14 is 451.21 g/mol.
Where can I buy Erlotinib Impurity 14?
You can request a quote for Erlotinib Impurity 14 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Erlotinib Impurity 14?
Yes, KEHONG BIO provides custom synthesis services for Erlotinib Impurity 14 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.