teniposide
TL;DR: teniposide (CAS 299-36-5) is a chemical compound with molecular formula C32H32O13S and molecular weight 656.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S,5aR,8aR,9R)-5-[(7,8-dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
Also Known As: teniposide, Teniposido, Teniposidum, Vehem, Vumon
| Molecular Formula | C32H32O13S |
|---|---|
| Molecular Weight | 656.16 g/mol |
| LogP | 1.2 |
| Topological Polar Surface Area | 189.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 656.1564 |
| Heavy Atoms | 46 |
| Complexity | 1090.0 |
Chemical Identifiers
| CAS Number | 299-36-5 |
|---|---|
| SMILES | COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O |
| InChIKey | NRUKOCRGYNPUPR-CRZAWEBOSA-N |
Product Overview
teniposide (CAS 299-36-5), with molecular formula C32H32O13S and molecular weight 656.16 g/mol. IUPAC: (5S,5aR,8aR,9R)-5-[(7,8-dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one.
Chemical Property Profile of teniposide
Property Insights of teniposide
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for teniposide. The TPSA of 189.0 Ų indicates high polarity, suggesting teniposide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, teniposide has 3 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of teniposide?
The CAS number of teniposide is 299-36-5.
What is the molecular formula of teniposide?
The molecular formula of teniposide is C32H32O13S.
What is the molecular weight of teniposide?
The molecular weight of teniposide is 656.16 g/mol.
Where can I buy teniposide?
You can request a quote for teniposide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for teniposide?
Yes, KEHONG BIO provides custom synthesis services for teniposide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.