Thiothiamine structure

Thiothiamine

TL;DR: Thiothiamine (CAS 299-35-4) is a chemical compound with molecular formula C12H16N4OS2 and molecular weight 296.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione

Also Known As: Thiothiamine, Thioxothiamine, Thiothiamin, sulbone, Fmrfamide

CAS: 299-35-4
Molecular Formula C12H16N4OS2
Molecular Weight 296.08 g/mol
LogP 0.8
Topological Polar Surface Area 133.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 296.07657
Heavy Atoms 19
Complexity 388.0

Chemical Identifiers

CAS Number 299-35-4
SMILES CC1=C(SC(=S)N1CC2=CN=C(N=C2N)C)CCO
InChIKey SQOCQQPFEFRKBV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Biotechnology (2 patents) Organic Building Blocks (1 patents)

Product Overview

Thiothiamine (CAS 299-35-4), with molecular formula C12H16N4OS2 and molecular weight 296.08 g/mol. IUPAC: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thiothiamine

XLogP
0.8
TPSA (Topological Polar Surface Area)
133.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
19
Complexity
388.0
Exact Mass
296.07657
Monoisotopic Mass
296.07657
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thiothiamine

The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Thiothiamine. The TPSA of 133.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiothiamine. Following Lipinski's Rule of Five, Thiothiamine has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thiothiamine?

The CAS number of Thiothiamine is 299-35-4.

What is the molecular formula of Thiothiamine?

The molecular formula of Thiothiamine is C12H16N4OS2.

What is the molecular weight of Thiothiamine?

The molecular weight of Thiothiamine is 296.08 g/mol.

Where can I buy Thiothiamine?

You can request a quote for Thiothiamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thiothiamine?

Yes, KEHONG BIO provides custom synthesis services for Thiothiamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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