SL327
TL;DR: SL327 (CAS 297744-39-9) is a chemical compound with molecular formula C16H12F3N3S and molecular weight 335.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
Also Known As: SL327, MEK1/2 Inhibitor, SL 327, Mek-1/Mek-2 Inhibitor, EX-A1069
| Molecular Formula | C16H12F3N3S |
|---|---|
| Molecular Weight | 335.07 g/mol |
| LogP | 4.23078 |
| Topological Polar Surface Area | 75.83 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 335.0704 |
| Heavy Atoms | 23 |
| Complexity | 774.3928 |
Chemical Identifiers
| CAS Number | 297744-39-9 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C(=C(\N)/SC2=CC=C(C=C2)N)/C#N)C(F)(F)F |
Product Overview
SL327 (CAS 297744-39-9), with molecular formula C16H12F3N3S and molecular weight 335.07 g/mol. IUPAC: (Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile.
Chemical Property Profile of SL327
Property Insights of SL327
The XLogP value of 4.23078 indicates that SL327 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.83 Ų falls within the moderate polarity range, balancing permeability and solubility for SL327. Following Lipinski's Rule of Five, SL327 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SL327?
The CAS number of SL327 is 297744-39-9.
What is the molecular formula of SL327?
The molecular formula of SL327 is C16H12F3N3S.
What is the molecular weight of SL327?
The molecular weight of SL327 is 335.07 g/mol.
Where can I buy SL327?
You can request a quote for SL327 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SL327?
Yes, KEHONG BIO provides custom synthesis services for SL327 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.