替尼泊甙
TL;DR: 替尼泊甙 (CAS 29767-20-2) is a chemical compound with molecular formula C32H32O13S and molecular weight 656.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
替尼泊甙
5-[(7,8-dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
Also Known As: teniposide, Vehem, Vumon, Teniposido, Teniposidum
| Molecular Formula | C32H32O13S |
|---|---|
| Molecular Weight | 656.16 g/mol |
| LogP | 1.2 |
| Topological Polar Surface Area | 189.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 656.1564 |
| Heavy Atoms | 46 |
| Complexity | 1090.0 |
Chemical Identifiers
| CAS Number | 29767-20-2 |
|---|---|
| SMILES | COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O |
| InChIKey | NRUKOCRGYNPUPR-UHFFFAOYSA-N |
Product Overview
替尼泊甙 (CAS 29767-20-2), with molecular formula C32H32O13S and molecular weight 656.16 g/mol. IUPAC: 5-[(7,8-dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one.
Chemical Property Profile of 替尼泊甙
Property Insights of 替尼泊甙
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 替尼泊甙. The TPSA of 189.0 Ų indicates high polarity, suggesting 替尼泊甙 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 替尼泊甙 has 3 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 替尼泊甙?
The CAS number of 替尼泊甙 is 29767-20-2.
What is the molecular formula of 替尼泊甙?
The molecular formula of 替尼泊甙 is C32H32O13S.
What is the molecular weight of 替尼泊甙?
The molecular weight of 替尼泊甙 is 656.16 g/mol.
Where can I buy 替尼泊甙?
You can request a quote for 替尼泊甙 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 替尼泊甙?
Yes, KEHONG BIO provides custom synthesis services for 替尼泊甙 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.