2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil
TL;DR: 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil (CAS 2968-28-7) is a chemical compound with molecular formula C9H11FN2O5 and molecular weight 246.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: floxuridine, SW220273-1, 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil, BRD-K73088654-001-01-9, 5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin
| Molecular Formula | C9H11FN2O5 |
|---|---|
| Molecular Weight | 246.07 g/mol |
| LogP | -1.6836 |
| Topological Polar Surface Area | 104.55 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.0652 |
| Heavy Atoms | 17 |
| Complexity | 524.8529 |
Chemical Identifiers
| CAS Number | 2968-28-7 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@@H]1N2C=C(C(=O)NC2=O)F)CO)O |
Product Overview
2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil (CAS 2968-28-7), with molecular formula C9H11FN2O5 and molecular weight 246.07 g/mol. IUPAC: 5-fluoro-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil
Property Insights of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil
The XLogP value of -1.6836 indicates that 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.55 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil. Following Lipinski's Rule of Five, 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil?
The CAS number of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil is 2968-28-7.
What is the molecular formula of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil?
The molecular formula of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil is C9H11FN2O5.
What is the molecular weight of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil?
The molecular weight of 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil is 246.07 g/mol.
Where can I buy 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil?
You can request a quote for 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil?
Yes, KEHONG BIO provides custom synthesis services for 2'-Deoxy-alpha-D-ribofuranosyl-5-fluorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.